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KMID : 0861020080230020137
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Korea Journal of Herbology
2008 Volume.23 No. 2 p.137 ~ p.143
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Effects of Herbal-cheonggukjang on Serum Composition and Urine in Rats
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Kim Hyung-Woo
Lee Sook-Young
Cho Soo-Jin
Jeong Sun
Cho Su-In
Kim Bu-Yeo
Park Jung-Suk
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Abstract
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Ojectives: Cheonggukjang(natto) is known to have anti-hyperlipidemic action in our previous study. This study was designed to investigate the safety of Prototype-cheonggukjang (PC, Herbal-natto).
Methods: We investigated the effects of PC on changes in body weights, food uptake, water uptake, levels of AST/ALT, levels of BUN/creatinine and electrolytes in serum from normal mice. PC is made by cheonggukjang added Codonopsis Lanceolata, Houttuynia cordata and Lentinus edodes in indicated concetrations.
Results: In this experiment, PC group showed equal levels of body weights, urine volume compared to non-treated control group. Oral administration of PC did not affect food and water uptake too. Levels of AST/ALT, which are markers of liver function, were not changed by administration of PC. In addition, levels of BUN/creatinine, which are markers of renal function, were not affected by PC too. Finally electrolytes in serum were not affected by PC.
Conclusions: These results imply that oral administration of PC is safe in the framework of liver and renal function, and electrolytes in serum
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KEYWORD
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Cheonggukjang, safety, herbal medicine
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